1 >>Iron absorption is increased in all, except: ?
- (A) Iron deficiency
- (B) Pregnancy
- (C) Hypoxia
- (D) Alkaline pH of stomach
2 >>All of the following in the diet leads to decreased iron absorption, except: ?
- (A) Oxalates
- (B) Ascorbate
- (C) Phytates
- (D) Phosphates
3 >>The earliest sign of iron deficiency anemia is: ?
- (A) Increased TIBC
- (B) Decreased S. iron
- (C) Decreased S. ferritin
- (D) Decreased % saturation
4 >>Which of the following is true about oral therapy for iron deficiency anemia? ?
- (A) If 300 mg elemental iron given only 100 mg gets absorbed
- (B) Reticulocytosis appears in 1-2 weeks and then peaks in 3-4 weeks
- (C) Hemoglobin levels are usually corrected in 6 weeks after starting therapy
- (D) Decrease in absorption of iron with improvement of Hb
5 >>A patient present with increased serum iron, decreased TIBC, increased percentage saturation and increased S. ferritin. Most likely diagnosis is: ?
- (A) Anemia of chronic disease
- (B) Sideroblastic anemia
- (C) Iron deficiency anemia
- (D) Thalassemia major
6 >>Features of Patterson-Kelly/Plummer-Vinson Syndrome includes all of the following, except: ?
- (A) Esophageal web in post-cricoid region
- (B) Iron deficiency
- (C) Koilonychia
- (D) Gum Hypertrophy
7 >>Macrocytic anemia may be seen with all of the following conditions,except: ?
- (A) Liver disease
- (B) Copper deficiency
- (C) Thiamine deficiency
- (D) Orotic aciduria
8 >>Anemia of chronic renal failure can be attributable to all of the following, except: ?
- (A) Low EPO level
- (B) Decreased RBC renewal
- (C) Decreased RBC supply
- (D) Decreased plasma volume
9 >>Erythropoietin levels will be low in all, except: ?
- (A) Polycythemia vera
- (B) Renal failure
- (C) AIHA
- (D) Anemia of chronic disease
10 >>Which is the first stage of iron deficiency? ?
- (A) Negative iron balance
- (B) Decreased iron stores
- (C) Decrease MCV
- (D) Decrease in Hemoglobin
11 >>Which statement is true regarding oral iron therapy? ?
- (A) Treatment should be given with alongwith vitamin C
- (B) Enteric coated and prolonged release preparations should be given
- (C) Best given after meals
- (D) Maximum dose is 200 mg of elemental iron/day
12 >>In which of the following conditions iron absorption will be increased? ?
- (A) Pregnancy
- (B) Chronic inflammation
- (C) Iron overload
- (D) Phosphates
13 >>Which of the following is not true about serum iron concentration? ?
- (A) It is low in anemia of chronic disease
- (B) Raised in hemochromatosis
- (C) Transported by ferritin
- (D) Shows a diurnal variation
14 >>Which of the following is true about methemoglobinemia? ?
- (A) Cyanosis due to abnormal Hb is inherited as autosomal recessive trait
- (B) Cyanosis due to NADH diaphorase deficiency is inherited as autosomal recessive trait
- (C) Most accurate method of diagnosing methemoglobinemia is by spectrophotometric analysis
- (D) Hereditary methemoglobinemia due to NADH-diaphorase deficiency is readily treated by ascorbic acid
15 >>When the circulating Hb in blood is present with iron in oxidized form (Fe3+) instead of Fe2+ state, it is called? ?
- (A) Methemoglobinuria
- (B) Methemoglobinemia
- (C) CDA
- (D) Carboxyhemoglobinemia
16 >>Acquired causes of a methemoglobinemia are: ?
- (A) Sulfonamide
- (B) Chloroquine
- (C) Dapsone
- (D) All of the above
17 >>Clinical manifestations of methemoglobinemia include: ?
- (A) Cyanosis
- (B) Hemolysis
- (C) Normal PaO2 in arterial blood gas analysis
- (D) All of the above
18 >>A 31 year-old man is brought to the emergency department after he had collapsed after a dental extraction in which prilocaine hydrochloride 3% was used as local anesthesia. The patient is deeply cyanosed despite a good respiratory effort, a clear airway, and bilateral clear breath sounds. Although he initially responds to vocal commands, his level of consciousness keeps on deteriorating. Oxygen saturation is 60% with the patient breathing room air. An endotracheal tube is introduced and assisted ventilation started, but this does not improve his cyanosis or level of consciousness.There was no family or personal history of such incidence. What is the treatment of this patient? ?
- (A) Exchange transfusion
- (B) Hyperbaric oxygen
- (C) Methylene blue
- (D) Dialysis
19 >>Hemolysis in G6PD is caused by all of the following, except: ?
- (A) Primaquine
- (B) Chloroquine
- (C) Pyrimethamine
- (D) Quinine
20 >>The most common cause of hereditary nonspherocytic hemolytic anemia: ?
- (A) G6PD deficiency
- (B) P K deficiency
- (C) Triosephosphate isomerase deficiency
- (D) None of the above
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